Experimental Design for the Life Sciences

Author: Graeme Ruxton,Nick Colegrave

Publisher: Oxford University Press

ISBN: 0199569126

Category: Education

Page: 178

View: 9254

Experimental Design for the Life Sciences teaches the reader how to effectively design experiments to ensure today's students are equipped with the skills they need to be the researchers of tomorrow. With a refreshingly approachable and articulate style, the book explains the essential elements of experimental design in clear, practical terms, so the reader can grasp and apply even the most challenging concepts, including power analysis andpseudoreplication. The inter-relatedness of experimental design, statistics, and ethical considerations is emphasised throughout the book and, above all, Experimental Design for the Life Sciencesdemonstrates how good experimental design relies on clear thinking and biological understanding, not mathematical or statistical complexity - putting it at the heart of any biosciences student's education.

Principles of Experimental Design for the Life Sciences

Author: Murray R. Selwyn

Publisher: CRC Press

ISBN: 9780849394614

Category: Science

Page: 176

View: 3096

Let this down-to-earth book be your guide to the statistical integrity of your work. Without relying on the detailed and complex mathematical explanations found in many other statistical texts, Principles of Experimental Design for the Life Sciences teaches how to design, conduct, and interpret top-notch life science studies. Learn about the planning of biomedical studies, the principles of statistical design, sample size estimation, common designs in biological experiments, sequential clinical trials, high dimensional designs and process optimization, and the correspondence between objectives, design, and analysis. Each of these important topics is presented in an understandable and non-technical manner, free of statistical jargon and formulas. Written by a biostatistical consultant with 25 years of experience, Principles of Experimental Design for the Life Sciences is filled with real-life examples from the author's work that you can quickly and easily apply to your own. These examples illustrate the main concepts of experimental design and cover a broad range of application areas in both clinical and nonclinical research. With this one innovative, helpful book you can improve your understanding of statistics, enhance your confidence in your results, and, at long last, shake off those statistical shackles!


Eine Einführung für Biologen und Agrarwissenschaftler

Author: Wolfgang Köhler,Gabriel Schachtel,Peter Voleske

Publisher: Springer-Verlag

ISBN: 3662061163

Category: Technology & Engineering

Page: 301

View: 5548

Diese bewährte und sehr gut verständliche Einführung in die Biometrie wurde für die Neuauflage überarbeitet und erweitert. Sie ist für all jene geeignet, die möglichst rasch statistische Verfahren zur Auswertung experimenteller Ergebnisse lernen und handhaben möchten. Grundlagen und Anwendung werden gleichermaßen dargestellt, wobei biologische und agrarwissenschaftliche Beispiele besonders berücksichtigt werden. Unter möglichst weitgehender Vermeidung von Formeln und mathematischer Symbolik wird dem Anwender zunächst ein Verständnis für die hinter dem Verfahren stehende Grundidee vermittelt. Übersichtliche Rechenanleitungen regen den Leser an, die Verfahren anhand der Beispieldaten wirklich nachzurechnen. Das Buch ist als Begleittext zu einer Vorlesung ebenso geeignet wie zum Selbststudium, um darauf aufbauend alleine oder mit dem Statistiker komplexe statistische Verfahren anzuwenden.

Experimental Design

Procedures for the Behavioral Sciences

Author: Roger E. Kirk

Publisher: SAGE Publications

ISBN: 1483305511

Category: Social Science

Page: 1072

View: 3393

Experimental Design: Procedures for Behavioral Sciences, Fourth Edition is a classic text with a reputuation for accessibility and readability. It has been revised and updated to make learning design concepts even easier. Roger E. Kirk shows how three simple experimental designs can be combined to form a variety of complex designs. He provides diagrams illustrating how subjects are assigned to treatments and treatment combinations. New terms are emphasized in boldface type, there are summaries of the advantages and disadvantages of each design, and real-life examples show how the designs are used.

Statistics Explained

An Introductory Guide for Life Scientists

Author: Steve McKillup

Publisher: Cambridge University Press

ISBN: 9781139445818

Category: Medical

Page: N.A

View: 7081

Statistics Explained is a reader-friendly introduction to experimental design and statistics for undergraduate students in the life sciences, particularly those who do not have a strong mathematical background. Hypothesis testing and experimental design are discussed first. Statistical tests are then explained using pictorial examples and a minimum of formulae. This class-tested approach, along with a well-structured set of diagnostic tables will give students the confidence to choose an appropriate test with which to analyse their own data sets. Presented in a lively and straight-forward manner, Statistics Explained will give readers the depth and background necessary to proceed to more advanced texts and applications. It will therefore be essential reading for all bioscience undergraduates, and will serve as a useful refresher course for more advanced students.

Experimental Design for Biologists

Author: David J. Glass

Publisher: N.A

ISBN: 9781621820413

Category: Science

Page: 294

View: 9249

"Experimental Design for Biologists is a unique and successful handbook on the theory and practice of effective design of scientific experiments, based on a well-received course by the author. This second edition is entirely reorganized, rewritten, and includes new material and figures. The material is presented in seven parts: Philosophy of Scientific Experimentation, Mapping Out the Project, System Validation, Experimental Design, Examples, What Comes After, and Putting It All Together. Experimental Design for Biologists, Second Edition, is an essential source in designing a sound research plan, critical to the success of graduate students"--

Experiment Design and Statistical Methods For Behavioural and Social Research

Author: David R. Boniface

Publisher: CRC Press

ISBN: 9780412542305

Category: Mathematics

Page: 272

View: 2021

Experiment Design and Statistical Methods introduces the concepts, principles, and techniques for carrying out a practical research project either in real world settings or laboratories - relevant to studies in psychology, education, life sciences, social sciences, medicine, and occupational and management research. The text covers: repeated measures unbalanced and non-randomized experiments and surveys choice of design adjustment for confounding variables model building and partition of variance covariance multiple regression Experiment Design and Statistical Methods contains a unique extension of the Venn diagram for understanding non-orthogonal design, and it includes exercises for developing the reader's confidence and competence. The book also examines advanced techniques for users of computer packages or data analysis, such as Minitab, SPSS, SAS, SuperANOVA, Statistica, BMPD, SYSTAT, Genstat, and GLIM.

Analysis of Variance and Covariance

How to Choose and Construct Models for the Life Sciences

Author: C. Patrick Doncaster,Andrew J. H. Davey

Publisher: Cambridge University Press

ISBN: 1139466224

Category: Medical

Page: N.A

View: 7350

Analysis of variance (ANOVA) is a core technique for analysing data in the Life Sciences. This reference book bridges the gap between statistical theory and practical data analysis by presenting a comprehensive set of tables for all standard models of analysis of variance and covariance with up to three treatment factors. The book will serve as a tool to help post-graduates and professionals define their hypotheses, design appropriate experiments, translate them into a statistical model, validate the output from statistics packages and verify results. The systematic layout makes it easy for readers to identify which types of model best fit the themes they are investigating, and to evaluate the strengths and weaknesses of alternative experimental designs. In addition, a concise introduction to the principles of analysis of variance and covariance is provided, alongside worked examples illustrating issues and decisions faced by analysts.

Effective Learning in the Life Sciences

How Students Can Achieve Their Full Potential

Author: David Adams

Publisher: John Wiley & Sons

ISBN: 1119977630

Category: Science

Page: 288

View: 6001

Effective Learning in the Life Sciences is intended to help ensure that each student achieves his or her true potential by learning how to solve problems creatively in laboratory, field or other workplace setting. Each chapter describes state of the art approaches to learning and teaching and will include case studies, worked examples and a section that lists additional online and other resources. All of the chapters are written from the perspective both of students and academics and emphasize and embrace effective scientific method throughout. This title also draws on experience from a major project conducted by the Centre for Bioscience, with a wide range of collaborators, designed to identify and implement creative teaching in bioscience laboratories and field settings. With a strong emphasis on students thinking for themselves and actively learning about their chosen subject Effective Learning in the Life Sciences provides an invaluable guide to making the university experience as effective as possible.

Der Ausdruck der Gemütsbewegungen beim Menschen und den Tieren

Author: Charles Darwin

Publisher: mach-mir-ein-ebook.de

ISBN: 394430943X

Category: Science

Page: 336

View: 9340

Bereits ein Jahr nach seinem grundlegenden Werk „Die Abstammung des Menschen und die geschlechtliche Zuchtwahl“ in dem Darwin seine Evolutionstheorie des Menschen erläuterte, erschien sein „Der Ausdruck der Gemütsbewegungen beim Menschen und den Tieren“, dass hiermit erstmals als E-Book in deutscher Sprache erscheint. In diesem Werk legt Darwin dar, dass auch die Gefühle und deren Ausdrucksweise sich bei Mensch und Tieren gleichen und wie äußere Merkmale durch Evolution entstanden sind. Er untersuchte unter anderem, ob die Art und Weise, wie die Aktivität der Gesichtsmuskeln des Menschen – die Mimik – seine Emotionen sichtbar macht, durch Lernen erworben oder vermutlich angeboren sei. Auch wies er auf zahlreiche Parallelen beim Ausdrucksverhalten von Mensch und Tier hin und deutete diese Übereinstimmungen als Stütze für seine Theorie einer Abstammung des Menschen und der Tiere von gemeinsamen Vorfahren. Seine Argumentation war von Beginn an umstritten, und sein Buch geriet für Jahrzehnte sogar nahezu in Vergessenheit. Wenige Monate nach Erscheinen wurden bereits 9000 Exemplare berkauift, danach geriet der Absatz jedoch ins Stocken. Eine zweite verbesserte Auflage wurde später kaum beachtet. In diesem Buch finden sich viele Beobachtungen und Erklärungen, die auch nach heutigem wissenschaftlichen Kenntnisstand zutreffend sind; andere sind völlig irrig; und es gibt einige über die sich die Wissenschaft bis heute streitet. Bereits im Jahr der englischen Erstausgabe erschien eine Übersetzung des deutschen Zoologen Victor Carus, die Grundlage dieses E-Book ist. Diese Übersetzung wurde modernisiert und in die neue deutsche Rechtschreibung übertragen.

Experimental Design for Laboratory Biologists

Maximising Information and Improving Reproducibility

Author: Stanley E. Lazic

Publisher: Cambridge University Press

ISBN: 1316810674

Category: Medical

Page: N.A

View: 496

Specifically intended for lab-based biomedical researchers, this practical guide shows how to design experiments that are reproducible, with low bias, high precision, and widely applicable results. With specific examples from research using both cell cultures and model organisms, it explores key ideas in experimental design, assesses common designs, and shows how to plan a successful experiment. It demonstrates how to control biological and technical factors that can introduce bias or add noise, and covers rarely discussed topics such as graphical data exploration, choosing outcome variables, data quality control checks, and data pre-processing. It also shows how to use R for analysis, and is designed for those with no prior experience. An accompanying website (https://stanlazic.github.io/EDLB.html) includes all R code, data sets, and the labstats R package. This is an ideal guide for anyone conducting lab-based biological research, from students to principle investigators working in either academia or industry.

Statistics and experimental design for behavioral and biological researchers

an introduction

Author: Victor H. Denenberg

Publisher: Halsted Press


Category: Science

Page: 344

View: 6422

What statistics is all about; Measurement: the choice of an endpoint; Descriptive statistics: frequency curves, averages, and variability; Making inferences about population parameters: general principles; The normal curve; The distribution; Comparing the means of an experimental and a control group; The analysis of variance: single classification; The analysis of variance: nested designs randomized blocks, and factorial experiments; Determining the linear relationship between variables: the correlation coefficient; Chi-square tests of nominal data; Order statistics for ranked data.

Experimental Design and Analysis in Animal Sciences

Author: Trevor Raymond Morris

Publisher: C A B International

ISBN: 9780851993492

Category: Science

Page: 208

View: 7228

Experimental Design and Analysis in Animals Sciences is the first book to provide detailed instructions on the design and analysis of experiments in animals sciences. Not only does it provide descriptions of the statistics of experiment design, this guide-book contains examples and suggestions that help students in their decisions on which tools are appropriate for each circumstance. The subjects covered include interpretation of dose-response experiments, change-over designs, experiments with animals in pens and paddocks, and balanced and unbalanced designs. This book will be indispensable for any graduate or advanced undergraduate student in the animal sciences.

The Design of Experiments in Neuroscience

Author: Mary Harrington

Publisher: SAGE

ISBN: 1412974321

Category: Medical

Page: 261

View: 3298

“You are about to start on a great adventure. You are going to transition from reading about science to becoming a scientist.” -From the Preface Using engaging, disarming prose, author Mary Harrington shows neuroscience students how to go about selecting a topic, designing an experiment, analyzing the results, and publishing a paper. This text effectively illustrates basic research methods and design principles by uniquely using relevant examples from neuroscience such as the principles of design of fMRI studies, the use of transgenic mice, and conditional gene knockouts. The author also addresses basic professional ethics, fundamental statistics and data analysis tools, the range of possible experimental designs (from simple descriptive studies to multifactorial designs), and ways to control unwanted variables and avoid common pitfalls. This text is intended as either a core or supplemental text for both undergraduates and graduate students studying research methods in Neuroscience, Neuroanatomy, Neurophysiology, Neurochemistry, or Biological Psychology.

Research Methodology in the Social, Behavioural and Life Sciences

Designs, Models and Methods

Author: Herman J Ader,Gideon J Mellenbergh

Publisher: SAGE

ISBN: 1446205282

Category: Social Science

Page: 416

View: 2400

This is an ideal text for advanced courses in research methods and experimental design. It argues that the methodology of quantitative research is a unified discipline with basic notions, procedures and ways of reasoning which can be applied across the social, behavioural and life sciences. Key designs, models and methods in research are covered by leading contributors in their field who seek to explain the fundamentals of the research process to enable the student to understand the broader implications and unifying themes.

Practical Statistics and Experimental Design for Plant and Crop Science

Author: Alan G. Clewer,David H. Scarisbrick

Publisher: John Wiley & Sons

ISBN: 1118685660

Category: Science

Page: 344

View: 7855

Presents readers with a user-friendly, non-technical introductionto statistics and the principles of plant and crop experimentation.Avoiding mathematical jargon, it explains how to plan and design anexperiment, analyse results, interpret computer output and presentfindings. Using specific crop and plant case studies, this guidepresents: * The reasoning behind each statistical method is explained beforegiving relevant, practical examples * Step-by-step calculations with examples linked to three computerpackages (MINITAB, GENSTAT and SAS) * Exercises at the end of many chapters * Advice on presenting results and report writing Written by experienced lecturers, this text will be invaluable toundergraduate and postgraduate students studying plant sciences,including plant and crop physiology, biotechnology, plant pathologyand agronomy, plus ecology and environmental science students andthose wanting a refresher or reference book in statistics.

Measuring Behaviour

An Introductory Guide

Author: Paul Martin,Patrick Bateson

Publisher: Cambridge University Press

ISBN: 1139643754

Category: Science

Page: N.A

View: 1307

Measuring Behaviour has established itself as a standard text. Largely rewritten, updated and reorganised, this third edition is, as before, a guide to the principles and methods of quantitative studies of behaviour, with an emphasis on techniques of observation, recording and analysis. It provides the basic knowledge needed to measure behaviour, doing so in a succinct and easily understood form. The sections on research design and the interpretation and presentation of data have been greatly expanded. Written with brevity and clarity, Measuring Behaviour is, above all, a practical guide book. Aimed primarily at undergraduate and graduate students in biology and psychology who are about to embark upon quantitative studies of animal and human behaviour, this book provides a concise review of methodology that will be of great value to scientists of all disciplines in which behaviour is measured, including biological anthropology, the social sciences and medicine.

Experimental Design for Formulation

Author: Wendell F. Smith

Publisher: SIAM

ISBN: 0898715806

Category: Science

Page: 367

View: 2655

Gender-Structured Population Modeling: Mathematical Methods, Numerics, and Simulations gives a unified presentation of and mathematical framework for modeling population growth by couple formation.