Nutritional Genomics

Discovering the Path to Personalized Nutrition

Author: Jim Kaput,Raymond L. Rodriguez

Publisher: John Wiley & Sons

ISBN: 0471781789

Category: Technology & Engineering

Page: 480

View: 4638

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The definitive guide to the basic principles and latest advances inNutritional Genomics Though still in its infancy, nutritional genomics, or"nutrigenomics," has revealed much about the complex interactionsbetween diet and genes. But it is in its potential applicationsthat nutrigenomics promises to revolutionize the ways we managehuman health and combat disease in the years ahead. Great progressalready has been made in modeling "personalized" nutrition foroptimal health and longevity as well as in genotype-based dietaryinterventions for the prevention, mitigation, or possible cure of avariety of chronic diseases and some types of cancer. Topics covered include: * Nutrients and gene expression * The role of metabolomics in individualized health * Molecular mechanisms of longevity regulation and calorierestriction * Green tea polyphenols and soy peptides in cancer prevention * Maternal nutrition and fetal gene expression * Genetic susceptibility to heterocyclic amines from cookedfoods * Bioinformatics and biocomputation in nutrigenomics * The pursuit of optimal diets Written by an all-star team of experts from around the globe, thisvolume provides an integrated overview of the cutting-edge field ofnutritional genomics. The authors and editors lead an in-depthdiscussion of the fundamental principles and scientificmethodologies that serve as the foundation for nutritional genomicsand explore important recent advances in an array of relateddisciplines. Each self-contained chapter builds upon itspredecessor, leading the reader seamlessly from basic principles tomore complex scientific findings and experimental designs.Scientific chapters are carefully balanced with those addressingthe social, ethical, regulatory, and commercial implications ofnutrigenomics.

Nutrition for a Better Life

A Journey from the Origins of Industrial Food Production to Nutrigenomics

Author: Peter Brabeck-Letmathe

Publisher: Campus Verlag

ISBN: 3593434571

Category: Business & Economics

Page: 220

View: 9129

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In Nutrition for a Better Life, one of the food industry's leading experts takes a factual look into the past and future of food and nutrition. Former Nestlé CEO Peter Brabeck-Letmathe shows that while in the past forty years convenience was the selling point for many industrially produced foods, consumers have now come to demand specifically healthy products. Going forward, it is health that will drive innovation in the industry. Using cutting-edge technology and scientifically based nutrition standards, the food industry will play a decisive role in improving the wellbeing of entire population groups, offering effective and cost-saving personalized diets that will both prevent and administer to the acute and chronic diseases of the twenty-first century.

Ernährung für ein besseres Leben

Eine Reise von den Anfängen der industriellen Nahrungsproduktion zur Nutrigenomik

Author: Peter Brabeck-Letmathe

Publisher: Campus Verlag

ISBN: 3593434563

Category: Business & Economics

Page: 250

View: 2442

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Wo die Lebensmittelindustrie ihre Zukunft sieht Durch die Fortschritte in den Biowissenschaften - vor allem der Genetik - sehen wir den Zusammenhang von Ernährung und Gesundheit heute in einem vollkommen neuen Licht. Wir können unsere Gesundheit und Lebensqualität nachhaltig optimieren, wenn wir unsere Ernährung auf wissenschaftlicher Grundlage neu gestalten. Peter Brabeck-Letmathe wirft einen Blick hinter die Kulissen der Forschung: Werden wir Zivilisationskrankheiten wie Bluthochdruck und Diabetes in Zukunft durch personalisierte Nahrungsmittel in den Griff bekommen? Dieses Buch verrät, woher die Lebensmittelindustrie weiß, was unseren Genen schmeckt.

Nutrition and Genomics

Issues of Ethics, Law, Regulation and Communication

Author: David Castle,Nola Ries

Publisher: Academic Press

ISBN: 9780080920825

Category: Technology & Engineering

Page: 312

View: 6342

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Nutrigenomics is the rapidly developing field of science that studies nutrient-gene interaction. This field has broad implications for understanding the interaction of human genomics and nutrition, but can also have very specific implications for individual dietary recommendations in light of personal genetics. Predicted applications for nutrigenomics include genomics-based dietary guidelines and personalized nutrition based on individual genetic tests. These developments have sweeping ethical, legal and regulatory implications for individuals, corporations and governments. This book brings together experts in ethics, law, regulatory analysis, and communication studies to identify and address relevant issues in the emerging field of nutritional genomics. Contributing authors are experts in the social aspects of biotechnology innovation, with expertise in nutrigenomics. From addressing the concern that nutrigenomics will transform food into medicine and undermine pleasures associated with eating to the latest in the science of nutrigenomics, this book provides a world-wide perspective on the potential impact of nutrigenomics on our association with food. *Explores the rapidly developing, yet not fully understood, impact of nutrigenomics on the relationship to food medicalization, genetic privacy, nutrition and health. *Provides ground for further exploration to identify issues and provide analysis to aid in policy and regulation development *Provides ethical and legal insights into this unfolding science, as well as serving as a model for thinking about issues arising in other fields of science and technology

Nutrigenomics and Nutrigenetics in Functional Foods and Personalized Nutrition

Author: Lynnette R. Ferguson

Publisher: CRC Press

ISBN: 1439876819

Category: Medical

Page: 451

View: 811

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While functional foods have become a reasonably well-established concept, personalized nutrition is still treated with skepticism by many. The recognition that people would have different nutrient requirements, or perceive foods in different ways, raises several concerns—some real, some not so real. Nutrigenomics and Nutrigenetics in Functional Foods and Personalized Nutrition addresses what is needed to bring nutrigenomics, nutrigenetics, and their associated technologies to market in a truly impactful way. Edited by Lynnette R. Ferguson, a well-known and internationally respected researcher, the book covers a wide range of issues, from the purely scientific to ethical, consumer-driven, and public health aspects. It takes a close look at gene–diet interactions and explores the ways in which studies on nutrigenomics and nutrigenetics can help modulate disease risk in cardiovascular disease, obesity, diabetes, and inflammatory bowel disease. Topics include regulatory challenges, genetic testing for consumers, data mining, transcriptomic analysis, and the role of science and health professionals in the commercialization of nutrigenomics and nutrigenetics. The book also examines industry–academia partnerships as a nexus between the science and its commercialization by the food industry. These partnerships will be an important determinant of what value the technologies bring, not only to the market but to the wider health and well-being of society. Exploring how nutrigenomics and nutrigenetics can help modulate disease risk, this timely book brings together stimulating, well-thought-out perspectives from established and emerging researchers. It provides valuable information on a subject that is becoming increasingly important for nutritionists, dieticians, and clinical professionals, as well as for the food industry and research community.

Nutrigenomics

Author: Gerald Rimbach,Jürgen Fuchs

Publisher: CRC Press

ISBN: 142002809X

Category: Medical

Page: 504

View: 4704

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Nutritional genomics, also referred to as nutrigenomics, is considered one of the next frontiers in the post-genomic era. Its fundamental premise is that while alterations in gene expression or epigenetic phenomena can subvert a healthy phenotype into manifesting chronic disease, through the introduction of certain nutrients, this process can be reversed or modified. Employing state-of-the-art genomic and proteomic investigations that monitor the expression of thousands of genes in response to diet, nutrigenomics investigates the occurrence of relationship between dietary nutrients and gene expression. Nutrigenomics was compiled to update the reader on recent advances in this emerging field. Over forty experts in nutrition, physiology, pathology, pharmacology, and the microbial sciences from all across the world present cutting-edge developments and emerging methods presently used in nutrigenomics. They include the latest studies and research on the role of oxidants, antioxidants, phytochemicals, and micronutrients in the modulation of gene expression affecting aging, immune function, carcinogenesis, and vascular health. As most human diseases are largely avoidable by lifestyle changes, this places nutrigenomics at the forefront of preventive medicine.

Nutrigenomics

Opportunities in Asia

Author: E. Shyong Tai,Peter J. Gillies

Publisher: Karger Medical and Scientific Publishers

ISBN: 3805582161

Category: Medical

Page: 248

View: 1874

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Nutrigenomics seeks to understand the variability of the individual's response to food and the underlying mechanisms whereby foods exert their health-promoting activities. With a deeper molecular understanding of nutrition, we may some day be able to design diets that truly maximize an individual's potential for health and wellness. Many Asian societies are currently experiencing a transition in diet-related morbidity and mortality. The identification and provision of an optimal diet relevant to all the people living in Asia is an extraordinary challenge as there exists a tremendous diversity in diet, dietary intake patterns, local culture, and nutritional needs. This volume explores the role of ethnic diversity, dietary patterns and genetic adaptation in determining individual nutrient requirements throughout the life-cycle. Conceptualized as an introductory publication providing a general overview as well as specific examples of the applications of concepts and methods, this publication will help scientists, medical, nutrition and other health professionals to learn more about the field of nutrigenomics.

Advances in Food Biochemistry

Author: Fatih Yildiz

Publisher: CRC Press

ISBN: 9781420007695

Category: Technology & Engineering

Page: 522

View: 9370

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Understanding the biochemistry of food is basic to all other research and development in the fields of food science, technology, and nutrition, and the past decade has seen accelerated progress in these areas. Advances in Food Biochemistry provides a unified exploration of foods from a biochemical perspective. Featuring illustrations to elucidate molecular concepts throughout the text, this volume examines a range of issues on the food spectrum, including: water and its relation to food the glycobiology of food components enzymes plant, animal, and human hormones functional foods, herbs, and dietary supplements flavor compounds in foods organic acids interactions between the environment with food components biological and lipid oxidation in foods food safety nutrition and the genetic makeup of individual food components Dr. Fatih Yildiz has published an extensive body of research and has worked on food and nutrition science projects with the FAO, UNIDO, UNICEF, and NATO. Recently he received the Ambassador for Turkey Award from the European Federation of Food Science and Technology. Dr. Yildiz and the contributors to this volume have brought together their decades of experience and expertise to provide a top-notch resource for food science and policy professionals and advanced students on the cutting edge of food research.

Nutrigenetics and Nutrigenomics

Author: Artemis P. Simopoulos,J. M. Ordovas

Publisher: Karger Medical and Scientific Publishers

ISBN: 3805577826

Category: Health & Fitness

Page: 324

View: 4550

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For the first time, international scientists describe the advances in genetics and nutrition by combining methods of molecular biology with those of functional genetics, also known as systems biology. This book provides the latest data on genetic variation and dietary response, nutrients and gene expression, and the contribution molecular biology has given to systems biology. It also includes a comprehensive critique of genetic association studies in defining the risk of chronic diseases and concludes that molecular diagnostic tests will eventually affect every area of health care from individual risk prediction, early diagnosis of disease, and determination of optimal treatment regimens, to monitoring treatment effectiveness. The appendix contains an extensive glossary of the newly emerging terminology, as well as recommendations for genetic screening. This publication is an essential tool for the future work of all physicians, nutritionists, dietitians, geneticists, physiologists, molecular biologists, anthropologists, food technologists, policy makers, ethicists and educators.

Food Science and Technology Bulletin

Functional Foods

Author: Glenn Gibson

Publisher: IFIS Publishing

ISBN: 0860141721

Category: Medical

Page: 104

View: 9058

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Food Science and Technology Bulletin: Functional Foods is an online minireview journal that delivers concise and relevant peer-reviewed minireviews of developments in selected areas of functional foods. Newly published minireviews are compiled to form an annual printed volume. Contents for Volume 3 of the Bulletin include minireviews on: Nutrigenomics - new frontiers in antioxidant research; Dietary fat composition and cardiovascular disease; Phytochemicals - a future in functional foods? Inulin: a prebiotic functional food ingredient; Assessment of the efficacy of probiotics, prebiotics and synbiotics in swine nutrition; Lactitol, an emerging prebiotic; Guidelines for an evidence-based review system for the scientific justification of diet and health relationships under Article 13 of the new European legislation on nutrition and health claims

Science, Society, and the Supermarket

The Opportunities and Challenges of Nutrigenomics

Author: David Castle,Cheryl Cline,Abdallah S. Daar,Charoula Tsamis,Peter A. Singer

Publisher: John Wiley & Sons

ISBN: 0470055499

Category: Technology & Engineering

Page: 192

View: 3123

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The new science of nutrigenomics and its ethical and societal challenges Gene-diet interactions--which underlie relatively benign lactose intolerance to life-threatening conditions such as cardiovascular disease--have long been known. But until now, scientists lacked the tools to fully understand the underlying mechanisms that cause these conditions. In recent years, however, strides in human genomics and the nutritional sciences have allowed for the advancement of a new science--dubbed nutrigenomics. Although this science may lead to personalized nutrition and dietary recommendations that can mitigate, prevent, or cure sickness, current oversight mechanisms and regulations for emerging direct-to-public nutrigenomic tests are still in their infancy. Science, Society, and the Supermarket: The Opportunities and Challenges of Nutrigenomics discusses the many ethical, legal, and social challenges presented by nutrigenomics. Concerning itself with the basic uses of nutrigenomic research as well as its clinical and commercial aspects, this text sheds light on such issues as: * Opportunities and challenges for nutrigenomics * The science of nutrigenomics * The ethics of nutrigenomic tests and information both in a clinical setting and by private third parties * Alternatives for nutrigenomics service delivery * Nutrigenomics and the regulation of health claims for foods and drugs * Equity and access to nutrigenomics in industrialized and developing countries * Intellectual property issues By taking a proactive bioethical stance on the subject, Science, Society, and the Supermarket offers a thorough and timely analysis on both the benefits and risks of nutrigenomics. Along with a thought-provoking examination of the issues, this book provides ethical guidelines and recommendations for further study in policy and regulatory development.

Personalized Nutrition

Translating Nutrigenetic/nutrigenomic Research Into Dietary Guidelines

Author: Artemis P. Simopoulos,John A. Milner

Publisher: Karger Medical and Scientific Publishers

ISBN: 3805594275

Category: Medical

Page: 180

View: 8604

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Awareness of the influence of our genetic variation to dietary response (nutrigenetics) and how nutrients may affect gene expression (nutrigenomics) is prompting a revolution in the field of nutrition. Nutrigenetics/Nutrigenomics provide powerful approaches to unravel the complex relationships among nutritional molecules, genetic variants and the biological system. This publication contains selected papers from the '3rd Congress of the International Society of Nutrigenetics/Nutrigenomics' held in Bethesda, Md., in October 2009. The contributions address frontiers in nutrigenetics, nutrigenomics, epigenetics, transcriptomics as well as non-coding RNAs and posttranslational gene regulations in various diseases and conditions. In addition to scientific studies, the challenges and opportunities facing governments, academia and the industry are included. Everyone interested in the future of personalized medicine and nutrition or agriculture, as well as researchers in academia, government and industry will find this publication of the utmost interest for their work.

Nutritional Genomics

Impact on Health and Disease

Author: Regina Brigelius-Flohé,Hans-Georg Joost

Publisher: John Wiley & Sons

ISBN: 3527607757

Category: Science

Page: 470

View: 5886

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Nutritional genomics paves the way for novel applications in medicine and human nutrition, and this volume presents the latest data on how genetic variation is associated with dietary response and how nutrients influence gene expression. In so doing, it brings together the various disciplines involved in this field of research, making this essential reading for nutritionists, biochemists and molecular biologists.

Nutrigenomics and Beyond

Informing the Future: Workshop Summary

Author: Institute of Medicine,Food and Nutrition Board

Publisher: National Academies Press

ISBN: 0309104890

Category: Science

Page: 90

View: 3131

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The integration of biology, genomics, and health has opened the possibility of applying genomics technology to nutrition. In 2001, scientists associated with the Human Genome Project announced the successful mapping of the reference sequence of the human genome. Since then, a body of information has emerged. Genomics and related areas of research have contributed greatly to efforts to understand the cellular and molecular mechanisms underlying diet-disease relationships. Integration and application of genetic and genomics technology into nutrition research is, therefore, needed to develop nutrition research programs that are aimed at the prevention and control of chronic disease through genomics-based nutritional interventions. Of interest is the integration of relevant computational methods into nutritional genomics research; the enhancement of tools applicable to systems biology; and the effective dissemination of genomics-derived information to scientists, policy makers, and the interested public. To address these issues, a workshop was held on June 1 and 2, 2006. The workshop included presentations that were structured around three focus sessions: human genetic variation, epigenetics, and systems biology. A fourth session presented discussions on the implications of nutrigenomics for the future of nutrition science research. Numerous themes emerged from the workshop presentations. First, nutrigenomics is a complex field because it addresses issues related to multigenetic traits that can be modified by a number of nutritional and other environmental factors. Such complexity presents a challenge to the field; and the ensuing research opportunities will require cooperative work among scientific disciplines and across government, academic, and industrial centers, as well as adequate funding, to be realized. Additionally, the ability to stretch the limits of conventional research methodologies afforded by new genetic and genomic applications at the level of the individual opens the door to a wealth of potential benefits to areas such as disease prevention and wellness, bearing in mind the necessity of ethical safeguards. This potential, however, must be wisely exploited to avoid the pitfalls of overpromising research results and prematurely setting unrealistic expectations for beneficial outcomes. Finally, careful and rigorous research must be employed to optimize outcomes and assure acceptance by the scientific community. In summary, nutrition science is uniquely poised to serve as the crossroads for many disciplines and, using genomics tools, can bring this knowledge together to better understand and address diet-related chronic diseases and molecular responses to dietary factors.

Recent Advances in Nutrigenetics and Nutrigenomics

Author: N.A

Publisher: Academic Press

ISBN: 012398405X

Category: Technology & Engineering

Page: 518

View: 394

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This volume of Progress in Molecular Biology and Translational Science covers the recent advances in the expanding fields of nutrigenetics and nutrigenomics. Forty authors from eight countries have contributed to the publication, representing the most cutting-edge research available. Contributions from leading authorities Informs and updates on all the latest developments in the field

Genomics and Proteomics in Nutrition

Author: Carolyn D. Berdanier,Naima Moustaid-Moussa

Publisher: CRC Press

ISBN: 9780203025925

Category: Medical

Page: 528

View: 1167

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With contributions from 66 world-renowned authorities on the subject, Genomics And Proteomics In Nutrition focuses on the effect of genetic expression on protein production, establishing links between gene expression and nutrition, the influence of micro- and macronutrients on cellular homeostasis, and the relationship between diet, genetic predisposition, and human disease. Shows how bioinformatics and functional genomic databases can transform molecular biology research using a yeast ELO2/ human HELO1 protein cloning example. A cutting-edge reference, Genomics and Proteomics in Nutrition reveals new applications and insights in nutrition science and explores tools for nutrition research in the post-genomic era.

Molecular Nutrition and Genomics

Nutrition and the Ascent of Humankind

Author: Mark Lucock

Publisher: John Wiley & Sons

ISBN: 9780470129371

Category: Medical

Page: 288

View: 7912

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This fascinating book draws it subject matter from a range of relevant disciplines that extend from molecular nutrition, nutritional sciences, and nutrition dietetics through to genetics, genomics, and anthropology. It presents a vital portrait of the absolutely fundamental role that nutrition has played and continues to play in shaping who and what human beings are, as well as where they evolved from, and where they may be heading as a species. Molecular Nutrition: Nutrition and the Evolution of Humankind: Blends coverage of the molecular mechanisms that underpin nutrient-gene interactions with evolutionary theory Takes a molecular biological approach to problem solving, and moves nutrition away from its dietetic and anthropological origins to the front lines of genomic research Covers key concepts in molecular biology; the –omics revolution and bioinformatics; recent human evolution; molecular mechanisms of gene-nutrient interactions; the importance of nutrients and genomics in disease; the evolution of micronutrient metabolism, protein structure, and human disease; nutrients and the human lifecycle; contemporary dietary patterns; leading-edge laboratory tools in nutrigenomics and human evolutionary studies Written by an internationally recognised expert in the field, Molecular Nutrition: Nutrition and the Evolution of Humankind is an invaluable text and reference book for a wide range of teachers, students, and researchers.

Processing and Nutrition of Fats and Oils

Author: N.A

Publisher: John Wiley & Sons

ISBN: 1118528786

Category: Technology & Engineering

Page: 276

View: 2382

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Processing and Nutrition of Fats and Oils reviewscurrent and new practices of fats and oils production. The bookexamines the different aspects of fats and oils processing, how thenutritional properties are affected, and how fats interact withother components and nutrients in food products. Coverage includescurrent trends in the consumption of edible fats and oils;properties of fats, oils and bioactive lipids; techniques toprocess and modify edible oils; nutritional aspects of lipids; andregulatory aspects, labeling and certifications of fats and oils infoods.

Nutritional Genomics - A Consumer's Guide to How Your Genes and Ancestry Respond to Food

Tailoring What You Eat to Your DNA

Author: Anne Hart

Publisher: iUniverse

ISBN: 0595290671

Category: Health & Fitness

Page: 372

View: 2699

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Learn to interpret the expression of your genes before you count your calories. If you're supposed to eat 'bright' for your 'genotype,' then you begin by mapping your genetic expression. Can the average consumer afford to find out what to eat for improved health and nourishment based upon tests of genetic expression? Can consumers override any inherited risks revealed in the genetic signature with foods and nutraceuticals individually tailored? What does it mean to eat 'smarter' foods that target specific genes? How do your genes respond to what you eat? There is a strong connection between nutrition and genotype, especially in regards to your cardiovascular and central nervous system health. So you need to tailor foods intelligently to your DNA. Match what you eat to your genetic expression. Genes are distributed, function, and work in such ways that nearly every reasonable diet could work well in about six percent of the population. Nutritional genomics, often abbreviated as 'nutrigenomics' is about increasing that success rate. How will science working together with the consumer tackle the issues confronting us as the population ages? Consumer involvement can democratize the science of nutritional genomics by improving diets for better health. You can ask to work on ethics boards or create your own. How is discovering deep ancestry through DNA testing related to the ways that food affects your health?

Textbook of Veterinary Internal Medicine - eBook

Author: Stephen J. Ettinger,Edward C. Feldman

Publisher: Elsevier Health Sciences

ISBN: 1437702821

Category: Medical

Page: 2208

View: 2419

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Now in its 7th edition, this popular, must-have text remains the only encyclopedic resource for veterinary internal medical problems. The internationally acclaimed "gold standard" offers unparalleled coverage of pathophysiology, diagnosis, and treatment of diseases affecting dogs and cats, as well as the latest information on the genome, clinical genomics, euthanasia, innocent heart murmurs, hyperbaric medicine, home prepared and raw diets, obesity, botulism, artificial pacing of the heart, cancer vaccines, and more. The 7th edition combines the convenience of a two-volume printed textbook with the enhanced functionality of an Expert Consult website that enables you to electronically search your entire book and study more efficiently. With instant access to the most reliable information available, you’ll always be at the forefront of veterinary care! Fully searchable online text provides fast, easy access to the most reliable information in the field. More than 150 clinical algorithms throughout the text aid in disease-identification and decision-making. Expanded online chapter content enhances your understanding through additional text, illustrations, tables, and boxes. Hyperlinked client information sheets streamline reference of specific conditions and enhance communication with clients. Extensive online reference list directs you to full-text PubMed abstracts for additional research. Thoroughly updated and expanded content, including 90 new chapters, addresses the latest developments across the full spectrum of small animal care. Companion Expert Consult website enhances your learning experience with the ability to search the entire electronic text instantly for easy reference. Expert Consult also gives you instant access to: More than 150 procedural videos that guide you step-by-step through essential procedures. Audio files that help you identify heart abnormalities by their sound.