Red Blood Cell Aging

Author: Antonio De Flora,Mauro Magnani

Publisher: Springer Science & Business Media

ISBN: 1468459856

Category: Medical

Page: 400

View: 4050

The mammalian erythrocyte is a very suitable model for the study of aging at the cellular and molecular level. It is not only a matter of apparent simplicity in terms of biochemistry, biophysics and physiology but more likely this cell offers a great possibility for elucidating some basic problems in the process of aging. In fact, nowadays, it is possible to follow individual cells all along their life span in circulation, it is possible to obtain these cells when young, middle aged or old and it is possible to obtain cells from individuals of defined ages and transfuse them into compatible recipients to investigate the role of the environment where the cell lives, and finally it is possible to easily manipulate the red cell content in terms of enzymatic activities and/or metabolic properties to investigate the possible effect of these manipulations on cell survival. This book, Red Blood Cell Aging, is based on a symposium held in Urbino, Italy, at the end of 1990 and examines the impact of age on the membrane, metabolism, structural and enzymatic proteins of mammalian erythrocytes. The various contributions to this symposium not only described those processes of aging which affect the cell but also provided a nearly complete picture of the event{s} and mechanism{s} that every day permits to recognize among 25 trillion circulating red cells {in an average adult} that 1 percent that have reached the end of their 120 day life span in circulation.

Life Itself

Exploring the Realm of the Living Cell

Author: Boyce Rensberger

Publisher: Oxford University Press, USA

ISBN: 9780195125009

Category: Science

Page: 290

View: 6812

In Life Itself, Boyce Rensberger, science writer for The Washington Post, takes readers to the frontlines of cell research with some of the brightest investigators in molecular, cellular, and developmental biology. Virtually all the hottest topics in biomedical research are covered here, such as how do cells and their minute components move? How do the body's cells heal wounds? What is cancer? Why do cells die? And what is the nature of life? Thesolutions to the most pressing challenges facing scientists today--from the efforts to conquer disease to the quest to understand life itself--will be found in the innermost workings of the cell. In Life Itself, Rensberger paints a colorful and fascinating portrait of modern research in this vital area, an accountwhich will enthrall anyone interested in state-of-the-art science or the incredible workings of the human body.

The Telomere Effect

A Revolutionary Approach to Living Younger, Healthier, Longer

Author: Dr. Elizabeth Blackburn,Dr. Elissa Epel

Publisher: Grand Central Publishing

ISBN: 1455587966

Category: Health & Fitness

Page: 302

View: 3761

NEW YORK TIMES BESTSELLER The revolutionary book coauthored by the Nobel Prize winner who discovered telomerase and telomeres' role in the aging process and the health psychologist who has done original research into how specific lifestyle and psychological habits can protect telomeres, slowing disease and improving life. Have you wondered why some sixty-year-olds look and feel like forty-year-olds and why some forty-year-olds look and feel like sixty-year-olds? While many factors contribute to aging and illness, Dr. Elizabeth Blackburn discovered a biological indicator called telomerase, the enzyme that replenishes telomeres, which protect our genetic heritage. Dr. Blackburn and Dr. Elissa Epel's research shows that the length and health of one's telomeres are a biological underpinning of the long-hypothesized mind-body connection. They and other scientists have found that changes we can make to our daily habits can protect our telomeres and increase our health spans (the number of years we remain healthy, active, and disease-free). THE TELOMERE EFFECT reveals how Blackburn and Epel's findings, together with research from colleagues around the world, cumulatively show that sleep quality, exercise, aspects of diet, and even certain chemicals profoundly affect our telomeres, and that chronic stress, negative thoughts, strained relationships, and even the wrong neighborhoods can eat away at them. Drawing from this scientific body of knowledge, they share lists of foods and suggest amounts and types of exercise that are healthy for our telomeres, mind tricks you can use to protect yourself from stress, and information about how to protect your children against developing shorter telomeres, from pregnancy through adolescence. And they describe how we can improve our health spans at the community level, with neighborhoods characterized by trust, green spaces, and safe streets. THE TELOMERE EFFECT will make you reassess how you live your life on a day-to-day basis. It is the first book to explain how we age at a cellular level and how we can make simple changes to keep our chromosomes and cells healthy, allowing us to stay disease-free longer and live more vital and meaningful lives.

The Language of the Genes

Author: Steve Jones

Publisher: HarperCollins UK

ISBN: 0007389272

Category: Science

Page: 352

View: 6899

Steve Jones’s highly acclaimed, double prize-winning, bestselling first book is now fully revised to cover all the new genetic breakthroughs from GM food to Dolly the sheep. ’An essential sightseer’s guide to our own genetic terrain.’ Peter Tallack, Sunday Telegraph

The Kaufmann Protocol

Why We Age and How to Stop It

Author: Sandra Kaufmann

Publisher: N.A

ISBN: 9780692089040

Category: Aging

Page: 332

View: 8584

"The Protocol is the first ever organized system that answers the question why we age as organisms. It offers a personalized program to legitimately curb the effects of time on the human body"--Page 4 of cover.

Library of Congress Subject Headings

Author: Library of Congress. Subject Cataloging Division

Publisher: Washington, D.C. : Cataloging Distribution Service, Library of Congress


Category: Subject headings, Library of Congress

Page: 4164

View: 5651


Concise encyclopedia of science and technology

Author: John-David Yule

Publisher: Crescent

ISBN: 9780517486108

Category: Science

Page: 590

View: 5702

A selective guide to the content, language, and history of science and technology, featuring investigations in astronomy, biology, chemistry, metallurgy, physics, geology, medicine, anthropology, psychology, linguistics, and philosophy

Library of Congress Subject Headings

Author: Library of Congress,Library of Congress. Subject Cataloging Division,Library of Congress. Office for Subject Cataloging Policy

Publisher: N.A


Category: Subject headings

Page: 2026

View: 1231


The End of Memory

A natural history of aging and Alzheimer’s

Author: Jay Ingram

Publisher: Random House

ISBN: 1473529654

Category: Health & Fitness

Page: 304

View: 5069

It has been called ‘the plague of the 21st century’ for its dramatic increase in numbers and the challenge it poses to health care. There are no effective treatments, merely a few drugs that promise only short-lived results. For centuries, those afflicted by Alzheimer's disease have been robbed of their memories and ability to think clearly; while families have watched their loved ones disappear day by day. In The End of Memory, award-winning author Jay Ingram charts the history of the disease, explaining the fascinating science behind it, recounting the efforts to understand and combat it, and introduces us to the passionate researchers who are working to find a cure. This is an important book for the millions of people around the world who are affected by Alzheimer’s, as well as those who are intrigued by both the ageing process and the brain, and wish to understand them better.

Principles of Regenerative Biology

Author: Bruce M. Carlson

Publisher: Elsevier

ISBN: 9780080477961

Category: Science

Page: 400

View: 2267

With the explosion of knowledge from molecular biology and the burgeoning interest in generating or regenerating tissues or organs through various bioengineering or stem cell approaches, many scientists and students have shown a renewed interest in the phenomenon of regeneration. Because relatively few have had the luxury of being able to approach the phenomenon of regeneration from a broad biological perspective, Dr. Carlson has produced a book that outlines the fundamental principles of regeneration biology. Subject matters focus principally on regeneration in vertebrate systems, but also invertebrate regeneration. In order to manipulate regenerative processes, it is important to understand the underlying principles of regeneration. Principles of Regnerative Biology is the key introductory reference for all developmental biologists, geneticists, and tissue and stem cell researchers. Creates a general understanding of one of the most fascinating and complex phenomena in biology Discusses the ability and diversity of regeneration in various organisms Explains the history and origins of cells in regenerating systems Includes information on stem cells and its important role in regeneration

Molecular Basis of Nutrition and Aging

A Volume in the Molecular Nutrition Series

Author: Marco Malavolta,Eugenio Mocchegiani

Publisher: Academic Press

ISBN: 0128018275

Category: Medical

Page: 784

View: 9432

Molecular Basis of Nutrition and Aging: A Volume in the Molecular Nutrition Series focuses on the nutritional issues associated with aging and the important metabolic consequences of diet, nutrition, and health. The book is subdivided into four parts that reflect the impact of nutrition from a biomolecular level to individual health. In Part One, chapters explore the general aspects of aging, aging phenotypes, and relevant aspects of nutrition related to the elderly and healthy aging. Part Two includes molecular and cellular targets of nutrition in aging, with chapters exploring lipid peroxidation, inflammaging, anabolic and catabolic signaling, epigenetics, DNA damage and repair, redox homeostasis, and insulin sensitivity, among others. Part Three looks at system-level and organ targets of nutrition in aging, including a variety of tissues, systems, and diseases, such as immune function, the cardiovascular system, the brain and dementia, muscle, bone, lung, and many others. Finally, Part Four focuses on the health effects of specific dietary compounds and dietary interventions in aging, including vitamin D, retinol, curcumin, folate, iron, potassium, calcium, magnesium, zinc, copper, selenium, iodine, vitamin B, fish oil, vitamin E, resveratrol, polyphenols, vegetables, and fruit, as well as the current nutritional recommendations. Offers updated information and a perspectives on important future developments to different professionals involved in the basic and clinical research on all major nutritional aspects of aging Explores how nutritional factors are involved in the pathogenesis of aging across body systems Investigates the molecular and genetic basis of aging and cellular senescence through the lens of the rapidly evolving field of molecular nutrition


The Science of Aging Backward

Author: Roderick Lane,Elizabeth Bright

Publisher: N.A

ISBN: 9781533045607


Page: 78

View: 9637

ReGeneration-X: The Science of Aging Backward. ReGeneration-X was formulated by two working naturopath's Roderick Lane ND and Elizabeth Bright ND. Roderick has a flourishing practice in the UK dealing with thyroid and endocrine issues. Elizabeth has a similar practice in Italy dealing with endocrine issues and naturopathic body adjustment. Roderick is the founder of the London College of Naturopathic medicine and also the author of numerous lectures and the Adam and Eve diet. Elizabeth speaks regularly on women's health issues and is the guest Naturopath on Mi Presento, Sono Donna!, a local television show dedicated to educating women about their health and natural solutions to their health. ReGeneration-X is unlike any other book about ketogenic diet you will come across. It was originally designed as a program of regeneration for a retired athlete who needed help prior to having surgery to replace his badly damaged hip, deal with his weight issues, high blood pressure and elevated cholesterol prior to the surgery. ReGeneration-X is actually based in the real-life situation of individuals seeking health and having actual health problems. Generation X, commonly abbreviated to Gen X, is the generation born after the Western Post-World War II baby boom. Most demographers and commentators use birth dates ranging from the early 1960s to the early 1980s. The first time the title was used was actually by the photographer Robert Capa in the early 1950s. ReGeneration-X is for those of us who have gone beyond youth but expect to have a youthful existence way beyond retirement, the question being if you're healthy and fit do you have to retire at all? Within its pages you will find a small part of the story of Pierre Mattia, the retired amateur cycling champion who raced in both Italy and the United States. The nutritional and dietary schedule that we produced for him was so successful that he encouraged us to actually write this book. So what is different, this book is based around real-life experiences of adults with health problems. Unlike a much of the information you will find on the internet this is not a diet for gym bunnies who are trying to strip off that last one percent of body fat to look highly sculptured in the gym, on the beach or at some body display exhibition. Regeneration-X is ketogenics for adults and athletes who can remember what it was like to be younger and fitter. Have you ever sat in front of the television and said to yourself, whilst watching a program, I can do that; only to remember that in fact you can't. The ReGeneration-X program or more correctly lifestyle is about regenerating and not degenerating you could say it is the graceful art of ageing backwards. People are always being told to lose weight, but how do you do it with ease and also deal with those other problems that occur when you are older? The answer is contained within the ReGeneration-X lifestyle program. The important bottom line is if you are seeking to return to health, control weight issues, get back the energy you once had, stabilise your blood sugar levels without resorting to massive drug intervention, the ReGeneration-X lifestyle program is for you because it works.

Life Ascending

The Ten Great Inventions of Evolution

Author: Nick Lane

Publisher: Profile Books

ISBN: 1847652220

Category: Science

Page: 469

View: 3374

Winner of the 2010 Royal Society Prize for science books Powerful new research methods are providing fresh and vivid insights into the makeup of life. Comparing gene sequences, examining the atomic structure of proteins and looking into the geochemistry of rocks have all helped to explain creation and evolution in more detail than ever before. Nick Lane uses the full extent of this new knowledge to describe the ten greatest inventions of life, based on their historical impact, role in living organisms today and relevance to current controversies. DNA, sex, sight and consciousnesses are just four examples. Lane also explains how these findings have come about, and the extent to which they can be relied upon. The result is a gripping and lucid account of the ingenuity of nature, and a book which is essential reading for anyone who has ever questioned the science behind the glories of everyday life.

Red Cell Membrane Transport in Health and Disease

Author: Ingolf Bernhardt,J. Clive Ellory

Publisher: Springer Science & Business Media

ISBN: 3662051818

Category: Science

Page: 748

View: 7474

51 worldwide leading experts in the field of erythrocyte research contributed to this first book on transport processes in red blood cells. It explains the latest findings on the basis of well-established principles, in an accessibly structured and carefully organized compilation.

Aging Without Growing Old

Author: Judy Lindberg McFarland,Laura Gladys McFarland

Publisher: Charisma Media

ISBN: 088419969X

Category: Health & Fitness

Page: 516

View: 4509

Most people today are aging too rapidly and are dying from illnesses that could be prevented! Judy Lindberg McFarland wants to help readers prevent all the degenerative diseases and illnesses that accompany aging and the heartaches resulting from the loss of one's health.In Aging Without Growing Old, men and women of all ages will find out how to become healthy through natural and nutritional means. They'll learn how to enjoy greater health no matter how old they are and how to slow the aging process down to a crawl. It is possible to start defying your age with the essential information found in this book!

The Red Blood Cell

Author: Douglas MacN. Surgenor

Publisher: Academic Press

ISBN: 1483257509

Category: Medical

Page: 782

View: 6098

The Red Blood Cell, Second Edition, Volume II provides a comprehensive treatment and review of basic biomedical knowledge about the circulating, adult red blood cell. This book discusses the transport through red cell membranes; carrier-mediated glucose transport across human red cell membranes; and metabolism of methemoglobin in human erythrocytes. The interaction of oxygen and carbon dioxide with hemoglobin at the molecular level; physiological role of the oxyhemoglobin dissociation curve; hemoglobinopathies; and thalassemia syndromes are also deliberated. This publication likewise covers the red cell genetic polymorphisms; biological life of the red cell; clinical indications for red cells and blood; and biophysical behavior of red cells in suspensions. Other topics include the electrokinetic behavior of red cells; erythrocyte as a biopsy tissue in the evaluation of nutritional status; and knowledge of red cell purine and pyrimidine metabolism coming from the study of human disease. This volume is recommended for students, researchers, teachers, and physicians aiming to acquire knowledge of the red blood cell.