Staphylococcus

Author: Greg A. Somerville

Publisher: Caister Academic Press

ISBN: 1910190500

Category: Medical

Page: 398

View: 4165

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In the twenty first century, the bacterium Staphylococcus aureus continues to be a global threat to human and animal health. There is currently no vaccine for preventing S. aureus infections and the bacterium has developed resistance to many, if not most, antibiotics, hence the therapeutic options are rapidly disappearing. The genetic and physiological flexibility that allows this commensal bacterium to become a powerful pathogen and elucidating the myriad of mechanisms it employs to avoid the host and/or antimicrobials are important areas of research. This book brings together respected S. aureus experts from around the world to provide a timely overview of staphylococcal research. Topics covered include: historical background; medical significance in humans and animals; genetic variation; virulence factors; metabolism and physiology; physiological proteomics; cell wall assembly and physiology; transition metal ion homeostasis; molecular strategies of antibiotic resistance; genetic regulation; and immune response. Essential reading for scientists working with staphylococci. This text is an excellent introduction for entry level scientists, as well as those seeking a deeper understanding of this critically important bacterial pathogen.

Staphylococcus

Molecular Genetics

Author: Jodi A. Lindsay

Publisher: Horizon Scientific Press

ISBN: 1904455298

Category: Science

Page: 278

View: 5077

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Focusing on the staphylococcal genetics, this title brings together the expertise and enthusiasm of an international panel of leading staphylococcal researchers to provide a state-of-the-art overview of the field.

The Staphylococci and staphylococcal pathogenesis

Author: David Heinrichs,Martin J. McGavin

Publisher: Frontiers E-books

ISBN: 2889190579

Category:

Page: N.A

View: 9069

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Members of the genus Staphylococcus play important roles in disease causation in humans and animals. Over the past decade, the completed sequencing of many staphylococcal genomes has contributed to a surge in the number of publications, which have promoted a tremendous advance in our knowledge of these important pathogens. Significant developments include the emergence of new and highly virulent strains of S. aureus, advances in tracking the evolution of human and animal adapted strains, a heightened appreciation of the role of mobile genetic elements in antibiotic resistance and pathogenesis, and important insights into staphylococcal physiology, immune evasion strategies, and cell surface proteins, as well as significant advances in vaccine development and therapeutics. This Research Topic will focus attention on the latest developments in these areas as they pertain to S. aureus and members of the coagulase-negative Staphylococci, and will also strive to identify areas of future development.

Staphylococci in Human Disease

Author: Kent B. Crossley,Kimberly K. Jefferson,Gordon L. Archer,Vance G. Fowler

Publisher: John Wiley & Sons

ISBN: 9781444308471

Category: Medical

Page: 640

View: 6846

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Staphylococci remain the most important cause of hospital-acquired infections in the U.S. and MRSA has become the most common cause of skin and soft tissue infection in many parts of the world. There is now a much greater understanding of the physiology and evolution of the staphylococci and this new edition reflects the rapid advancements in knowledge about this pathogen and provides a comprehensive review from both clinical and basic science perspectives. The first section addresses the basic biology of the staphylococci, their molecular genetics, host defenses and host evasion, virulence determinants, mechanisms of antibiotic resistance, and laboratory techniques. The second section deals with epidemiology, and the third section provides an overview of the varied clinical manifestations of human staphylococcal infections. The fourth section covers prevention and treatment of these often life-threatening infections. Written by experts from around the globe, this book is essential reading for all clinicians and basic scientists studying the staphylococci.

Brewing Microbiology

Author: Nicholas A. Bokulich

Publisher: Caister Academic Press

ISBN: 1910190624

Category: Science

Page: 338

View: 8200

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Research into brewing yeast and other organisms associated with beer and brewing has experienced many important advances in the past decade, propelled by technological advances in tools fundamental to the investigation of microbes and their metabolism. This volume surveys the most recent discoveries in brewing microbiology, with an emphasis on omics techniques and other modern technologies. Discoveries in these areas have furthered our knowledge of brewing processes, with practical applications from barley growth and malting to yeast management, strain selection, fermentation control, and quality assurance. The chapters, written by experts in the field, aim not only to illuminate recent progress, but also to discuss its impact on brewing practices. Topics covered include the physiology, fermentation, taxonomy, diversity, typing, genetic manipulation, genomics and evolution of brewing yeasts. Further areas covered include the fungal contamination of barley and malt, spoilage by lactic acid bacteria and gram-negative bacteria, and beer-spoiling yeasts. This volume is highly recommended for anyone involved in the microbiology of brewing.

Molecular Medical Microbiology, Three-Volume Set

Author: Yi-Wei Tang,Dongyou Liu,Ian Poxton,Joseph Schwartzman,Max Sussman

Publisher: Elsevier

ISBN: 0080536883

Category: Science

Page: 2223

View: 1238

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The molecular age has brought about dramatic changes in medical microbiology, and great leaps in our understanding of the mechanisms of infectious disease. Molecular Medical Microbiology is the first book to synthesise the many new developments in both molecular and clinical research in a single comprehensive resource. This timely and authoritative 3-volume work is an invaluable reference source of medical bacteriology. Comprising over 100 chapters, organised into 17 major sections, the scope of this impressive work is wide-ranging. Written by experts in the field, chapters include cutting edge information, and clinical overviews for each major bacterial group, in addition to the latest updates on vaccine development, molecular technology and diagnostic technology. * The first comprehensive and accessible reference on Molecular Medical Microbiology * Two color presentation throughout * Full colour plate section * Fully integrated and meticulously organised * In depth discussion of individual pathogenic bacteria in a system-oriented approach * Includes a clinical overview for each major bacterial group * Presents the latest information on vaccine development, molecular technology and diagnostic technology * Extensive indexing and cross-referencing throughout * Over 100 chapters covering all major groups of bacteria * Written by an international panel of authors expert in their respective disciplines * Over 2300 pages in three volumes

Helicobacter Pylori

Molecular Genetics and Cellular Biology

Author: Yoshio Yamaoka

Publisher: Horizon Scientific Press

ISBN: 190445531X

Category: Medical

Page: 261

View: 3519

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Helicobacter pylori is an important human pathogen that infects up to 50% of the human population. As the leading cause of peptic ulcers, gastritis, and gastric cancer worldwide, the organism has been the subject of intensive research to unravel the mysteries of its genetics and cellular biology. In fact, the number of publications in this field has risen dramatically in recent years making it extremely difficult for even the most diligent reader to stay abreast of progress. This book distills the most important cutting-edge findings in the field to produce a timely and comprehensive review. With contributions from leading international helicobacter researchers, topics include: lipopolysaccharides, outer membrane proteins, motility and chemotaxis, type IV secretions systems, metal metabolism, molecular mechanisms of host adaptation, genomotyping, and proteonomics. As a useful introduction to the subject for new researchers and as an invaluable reference for the experienced researcher, this book is essential reading for all researchers working with Helicobacter and related organisms.

Metagenomics

Author: Diana Marco

Publisher: Caister Academic Press

ISBN: 1910190608

Category: Science

Page: 152

View: 8634

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Metagenomics continues to be one of the most dynamic scientific fields due largely to the development of new and cheaper sequencing technologies. The diversity of habitats explored with metagenomics and other meta-omics techniques has increased exponentially in recent years. The resulting cascade of data has led to a new range of methodological problems and solutions. In this collection of reviews, expert authors describe the cutting-edge and emerging conceptual and methodological tools being employed to deal with current issues in metagenomics. Topics covered include the integration of ecology and metagenomics; the organization, classification, analysis and interpretation of the vast amount of data; the new statistical and bioinformatic techniques; sample extraction and processing techniques; and various applications of metagenomics in specific areas. The volume is essential reading for researchers and students commencing projects in this field, for researchers active in metagenomics areas, and for educators interested in the latest developments. The volume is also of value to anyone involved in biotechnology, bioremediation, biodegradation and environmental microbiology.

Clostridia

Molecular Biology in the Post-genomic Era

Author: Holger Brüggemann,Gerhard Gottschalk

Publisher: Horizon Scientific Press

ISBN: 1904455387

Category: Science

Page: 230

View: 2993

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"In this book internationally recognized Clostridium experts critically review the most important aspects of clostridial research, providing the first coherent picture of the organism's molecular and cellular biology in this post-genomic era. Essential reading for every clostridia researcher, from the PhD student to the experienced scientist, as it provides a timely review of current research." --Book Jacket.

Genetics and Evolution of Infectious Diseases

Author: Michel Tibayrenc

Publisher: Elsevier

ISBN: 9780123848901

Category: Medical

Page: 749

View: 9811

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This multidisciplinary book is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious diseases are indisputably the major challenge of medicine. When looking globally, they are the number one killer of humans and therefore the main selective pressure exerted on our species. Even in industrial countries, infectious diseases are now far less under control than 20 years ago. The first part of this book covers the main features and applications of modern technologies in the study of infectious diseases. The second part provides detailed information on a number of the key infectious diseases such as malaria, SARS, avian flu, HIV, tuberculosis, nosocomial infections and a few other pathogens that will be taken as examples to illustrate the power of modern technologies and the value of evolutionary approaches. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field

Food Microbiology

Fundamentals and Frontiers

Author: Michael P. Doyle,Robert L. Buchanan

Publisher: American Society for Microbiology Press

ISBN: 1555816266

Category: Science

Page: 1138

View: 7454

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This essential reference emphasizes the molecular and mechanistic aspects of food microbiology in one comprehensive volume. • Addresses the field's major concerns, including spoilage, pathogenic bacteria, mycotoxigenic molds, viruses, prions, parasites, preservation methods, fermentation, beneficial microorganisms, and food safety. • Details the latest scientific knowledge and concerns of food microbiology • Offers a description of the latest and most advanced techniques for detecting, analyzing, tracking, and controlling microbiological hazards in food. • Serves as significant reference book for professionals who conduct research, teach food microbiology courses, analyze food samples, conduct epidemiologic investigations, and craft food safety policies.

Helicobacter Pylori

Physiology and Genetics

Author: Harry L. T. Mobley,George L. Mendz,Stuart L. Hazell

Publisher: Amer Society for Microbiology

ISBN: 9781555812133

Category: Medical

Page: 608

View: 8730

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A comprehensive survey of Helicobacter biology. Offers information ranging from fundamental bacteriology through energy metabolism and synthetic pathways, physiology and molecular biology, genetics, epidemiology, virulence and pathogenic mechanisms, pathogenesis in the host, diagnosis and treatment, and the relationship between Helicobacter pylori and other Helicobacter species."

Bifidobacteria

Genomics and Molecular Aspects

Author: Baltasar Mayo,Douwe van Sinderen

Publisher: Horizon Scientific Press

ISBN: 1904455689

Category: Science

Page: 259

View: 1103

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This title brings together the expertise of leading bifidobacteria experts from around the world to provide an overview of the molecular biology and genomics of this important microbial genus.

Anatomy ;Ocular physiology ;Biochemistry and genetics ;Pathology ;Microbiology ;Immunology ;Growth and senescence ;Optics ;Therapeutics ;Lasers and instrument technology ;Basic biostatistical and epidemiological terms

Author: Louise Bye,Neil Modi,Miles Stanford

Publisher: OUP Oxford

ISBN: 0199584990

Category: Medical

Page: 288

View: 6636

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An indispensable and fully comprehensive textbook, this covers the basic sciences in ophthalmology and is the only book you need to pass the FRCOphth Part 1 exam.

Gram-positive Pathogens

Author: Vincent A. Fischetti

Publisher: ASM Press

ISBN: 1555813437

Category: Medical

Page: 849

View: 8507

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Provides comprehensive coverage of all gram-positive pathogens, including genome data. Appeals to clinicians, infectious disease specialists, and instructors and students seeking a single reference source on gram-positive bacteria.

Microbial Population Genetics

Author: Jianping Xu

Publisher: Horizon Scientific Press

ISBN: 190445559X

Category: Science

Page: 213

View: 2536

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Microbial population genetics is a rapidly advancing field of investigation with relevance to many areas of science. The subject encompasses theoretical issues, such as the origins and evolution of species, sex, and recombination. Population genetics lays the foundations for tracking the origin and evolution of antibiotic resistance and deadly infectious pathogens and is also an essential tool in the utilization of beneficial microbes. This invaluable book, written by leading researchers in the field, details the current major advances in microbial population genetics and genomics. Distinguished international scientists introduce fundamental concepts, describe genetic tools, and comprehensively review recent data from SNP surveys, whole-genome DNA sequences, and microarray hybridizations. The chapters cover broad groups of microorganisms including viruses, bacteria, archaea, fungi, protozoa, and algae. A major focus is the application of molecular tools in the study of genetic variation. Topics covered include microbial systematics, comparative microbial genomics, horizontal gene transfer, pathogenic bacteria, nitrogen-fixing bacteria, cyanobacteria, microalgae, fungi, malaria parasites, viral pathogens, and metagenomics. Microbial Population Genetics is an essential volume for everyone interested in population genetics, and it is highly recommended reading for all microbiologists.

Environmental Molecular Microbiology

Author: Wen-Tso Liu,Janet K. Jansson

Publisher: Horizon Scientific Press

ISBN: 1904455522

Category: Science

Page: 231

View: 3650

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This book highlights the current state-of-the-art of environmental molecular microbiology. International experts have contributed chapters that describe the various technologies and their applications in environmental microbiology.

Methods for General and Molecular Microbiology

Author: C. A. Reddy,Terry J. Beveridge,John A. Breznak,George Marzluf

Publisher: American Society for Microbiology Press

ISBN: 1555812236

Category: Science

Page: 1069

View: 6260

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A first source for traditional methods of microbiology as well as commonly used modern molecular microbiological methods. • Provides a comprehensive compendium of methods used in general and molecular microbiology. • Contains many new and expanded chapters, including a section on the newly important field of community and genomic analysis. • Provides step-by-step coverage of procedures, with an extensive list of references to guide the user to the original literature for more complete descriptions. • Presents methods for bacteria, archaea, and for the first time a section on mycology. • Numerous schematics and illustrations (both color and black and white) help the reader to easily understand the topics presented.

Pet-to-Man Travelling Staphylococci

A World in Progress

Author: Vincenzo Savini

Publisher: Academic Press

ISBN: 0128135484

Category: Science

Page: 322

View: 2659

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Pet-to-Man Travelling Staphylococci: A World in Progress explores Staphylococci, a dangerous pathogen that affects both humans and animals with a wide range of infection states. This bacteria can spread rapidly as a commensal organism in both humans and pets, and is an agent of disease. Staphylococci are potentially highly virulent pathogens which require urgent medical attention. In addition, Staphylococci remain a threat within hospital environments, where they can quickly spread across a patient population. This book explores the organisms' resistance to many compounds used to treat them, treatment failure and multidrug resistant staphylococci, amongst other related topics. Focuses not only on man and animal staphylococcal diseases, but on the role of shared household in man-to-pet (and vice versa) transmission Underlines the importance of professional exposure to mammals (i.e. veterinary and farm personnel) in the establishment of shared colonization's and related diseases Highlights the impact of shared staphylococci and virulence determinants in human and veterinary pathology Sheds light on the way staphylococci may be recognized in clinical laboratories

Physiology and Genetics

Selected Basic and Applied Aspects

Author: Timm Anke,Daniela Weber

Publisher: Springer Science & Business Media

ISBN: 9783642002861

Category: Science

Page: 410

View: 8627

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In the last decade the discipline of mycology has been substantially changed by new research technologies. In particular DNA-based tools for the investigation of fungal taxonomy, signal transduction and regulation, and biosynthetic potential have accelerated advances in mycological knowledge. This volume presents a selection of exciting issues on basic and applied aspects of fungal physiology and genetics. In 18 chapters renowned experts provide an overview of traditional as well as current and future aspects of potential application of fungi in biotechnology. The contributions can be used by scientists to keep up-to-date on the latest developments in the corresponding research area, and by students to familiarize themselves with the different topics.