Staphylococcus

Author: Greg A. Somerville

Publisher: Caister Academic Press

ISBN: 1910190500

Category: Medical

Page: 398

View: 5046

DOWNLOAD NOW »
In the twenty first century, the bacterium Staphylococcus aureus continues to be a global threat to human and animal health. There is currently no vaccine for preventing S. aureus infections and the bacterium has developed resistance to many, if not most, antibiotics, hence the therapeutic options are rapidly disappearing. The genetic and physiological flexibility that allows this commensal bacterium to become a powerful pathogen and elucidating the myriad of mechanisms it employs to avoid the host and/or antimicrobials are important areas of research. This book brings together respected S. aureus experts from around the world to provide a timely overview of staphylococcal research. Topics covered include: historical background; medical significance in humans and animals; genetic variation; virulence factors; metabolism and physiology; physiological proteomics; cell wall assembly and physiology; transition metal ion homeostasis; molecular strategies of antibiotic resistance; genetic regulation; and immune response. Essential reading for scientists working with staphylococci. This text is an excellent introduction for entry level scientists, as well as those seeking a deeper understanding of this critically important bacterial pathogen.

Staphylococcus

Molecular Genetics

Author: Jodi A. Lindsay

Publisher: Horizon Scientific Press

ISBN: 1904455298

Category: Science

Page: 278

View: 5946

DOWNLOAD NOW »
Focusing on the staphylococcal genetics, this title brings together the expertise and enthusiasm of an international panel of leading staphylococcal researchers to provide a state-of-the-art overview of the field.

Staphylococci in Human Disease

Author: Kent B. Crossley,Kimberly K. Jefferson,Gordon L. Archer,Vance G. Fowler

Publisher: John Wiley & Sons

ISBN: 9781444308471

Category: Medical

Page: 640

View: 9175

DOWNLOAD NOW »
Staphylococci remain the most important cause of hospital-acquired infections in the U.S. and MRSA has become the most common cause of skin and soft tissue infection in many parts of the world. There is now a much greater understanding of the physiology and evolution of the staphylococci and this new edition reflects the rapid advancements in knowledge about this pathogen and provides a comprehensive review from both clinical and basic science perspectives. The first section addresses the basic biology of the staphylococci, their molecular genetics, host defenses and host evasion, virulence determinants, mechanisms of antibiotic resistance, and laboratory techniques. The second section deals with epidemiology, and the third section provides an overview of the varied clinical manifestations of human staphylococcal infections. The fourth section covers prevention and treatment of these often life-threatening infections. Written by experts from around the globe, this book is essential reading for all clinicians and basic scientists studying the staphylococci.

Genetics and Evolution of Infectious Diseases

Author: Michel Tibayrenc

Publisher: Elsevier

ISBN: 0128001534

Category: Medical

Page: 686

View: 6807

DOWNLOAD NOW »
Genetics and Evolution of Infectious Diseases, Second Edition, discusses the constantly evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world. Students in public health, biomedical professionals, clinicians, public health practitioners, and decisions-makers will find valuable information in this book that is relevant to the control and prevention of neglected and emerging worldwide diseases that are a major cause of global morbidity, disability, and mortality. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases during the last century, in recent decades the world has witnessed a worldwide human immunodeficiency virus (HIV) pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. The economic, social, and political burden of infectious diseases is most evident in developing countries which must confront the dual burden of death and disability due to infectious and chronic illnesses. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field of infectious disease

Brewing Microbiology

Author: Nicholas A. Bokulich

Publisher: Caister Academic Press

ISBN: 1910190624

Category: Science

Page: 338

View: 1930

DOWNLOAD NOW »
Research into brewing yeast and other organisms associated with beer and brewing has experienced many important advances in the past decade, propelled by technological advances in tools fundamental to the investigation of microbes and their metabolism. This volume surveys the most recent discoveries in brewing microbiology, with an emphasis on omics techniques and other modern technologies. Discoveries in these areas have furthered our knowledge of brewing processes, with practical applications from barley growth and malting to yeast management, strain selection, fermentation control, and quality assurance. The chapters, written by experts in the field, aim not only to illuminate recent progress, but also to discuss its impact on brewing practices. Topics covered include the physiology, fermentation, taxonomy, diversity, typing, genetic manipulation, genomics and evolution of brewing yeasts. Further areas covered include the fungal contamination of barley and malt, spoilage by lactic acid bacteria and gram-negative bacteria, and beer-spoiling yeasts. This volume is highly recommended for anyone involved in the microbiology of brewing.

Metagenomics

Author: Diana Marco

Publisher: Caister Academic Press

ISBN: 1910190608

Category: Science

Page: 152

View: 3214

DOWNLOAD NOW »
Metagenomics continues to be one of the most dynamic scientific fields due largely to the development of new and cheaper sequencing technologies. The diversity of habitats explored with metagenomics and other meta-omics techniques has increased exponentially in recent years. The resulting cascade of data has led to a new range of methodological problems and solutions. In this collection of reviews, expert authors describe the cutting-edge and emerging conceptual and methodological tools being employed to deal with current issues in metagenomics. Topics covered include the integration of ecology and metagenomics; the organization, classification, analysis and interpretation of the vast amount of data; the new statistical and bioinformatic techniques; sample extraction and processing techniques; and various applications of metagenomics in specific areas. The volume is essential reading for researchers and students commencing projects in this field, for researchers active in metagenomics areas, and for educators interested in the latest developments. The volume is also of value to anyone involved in biotechnology, bioremediation, biodegradation and environmental microbiology.

Molecular Medical Microbiology, Three-Volume Set

Author: Yi-Wei Tang,Dongyou Liu,Ian Poxton,Joseph Schwartzman,Max Sussman

Publisher: Elsevier

ISBN: 0080536883

Category: Science

Page: 2223

View: 9354

DOWNLOAD NOW »
The molecular age has brought about dramatic changes in medical microbiology, and great leaps in our understanding of the mechanisms of infectious disease. Molecular Medical Microbiology is the first book to synthesise the many new developments in both molecular and clinical research in a single comprehensive resource. This timely and authoritative 3-volume work is an invaluable reference source of medical bacteriology. Comprising over 100 chapters, organised into 17 major sections, the scope of this impressive work is wide-ranging. Written by experts in the field, chapters include cutting edge information, and clinical overviews for each major bacterial group, in addition to the latest updates on vaccine development, molecular technology and diagnostic technology. * The first comprehensive and accessible reference on Molecular Medical Microbiology * Two color presentation throughout * Full colour plate section * Fully integrated and meticulously organised * In depth discussion of individual pathogenic bacteria in a system-oriented approach * Includes a clinical overview for each major bacterial group * Presents the latest information on vaccine development, molecular technology and diagnostic technology * Extensive indexing and cross-referencing throughout * Over 100 chapters covering all major groups of bacteria * Written by an international panel of authors expert in their respective disciplines * Over 2300 pages in three volumes

Helicobacter Pylori

Molecular Genetics and Cellular Biology

Author: Yoshio Yamaoka

Publisher: Horizon Scientific Press

ISBN: 190445531X

Category: Medical

Page: 261

View: 970

DOWNLOAD NOW »
Helicobacter pylori is an important human pathogen that infects up to 50% of the human population. As the leading cause of peptic ulcers, gastritis, and gastric cancer worldwide, the organism has been the subject of intensive research to unravel the mysteries of its genetics and cellular biology. In fact, the number of publications in this field has risen dramatically in recent years making it extremely difficult for even the most diligent reader to stay abreast of progress. This book distills the most important cutting-edge findings in the field to produce a timely and comprehensive review. With contributions from leading international helicobacter researchers, topics include: lipopolysaccharides, outer membrane proteins, motility and chemotaxis, type IV secretions systems, metal metabolism, molecular mechanisms of host adaptation, genomotyping, and proteonomics. As a useful introduction to the subject for new researchers and as an invaluable reference for the experienced researcher, this book is essential reading for all researchers working with Helicobacter and related organisms.

Pet-to-Man Travelling Staphylococci

A World in Progress

Author: Vincenzo Savini

Publisher: Academic Press

ISBN: 0128135484

Category: Science

Page: 322

View: 632

DOWNLOAD NOW »
Pet-to-Man Travelling Staphylococci: A World in Progress explores Staphylococci, a dangerous pathogen that affects both humans and animals with a wide range of infection states. This bacteria can spread rapidly as a commensal organism in both humans and pets, and is an agent of disease. Staphylococci are potentially highly virulent pathogens which require urgent medical attention. In addition, Staphylococci remain a threat within hospital environments, where they can quickly spread across a patient population. This book explores the organisms' resistance to many compounds used to treat them, treatment failure and multidrug resistant staphylococci, amongst other related topics. Focuses not only on man and animal staphylococcal diseases, but on the role of shared household in man-to-pet (and vice versa) transmission Underlines the importance of professional exposure to mammals (i.e. veterinary and farm personnel) in the establishment of shared colonization's and related diseases Highlights the impact of shared staphylococci and virulence determinants in human and veterinary pathology Sheds light on the way staphylococci may be recognized in clinical laboratories

Molecular, Genetic, and Nutritional Aspects of Major and Trace Minerals

Author: James F Collins

Publisher: Academic Press

ISBN: 0128023767

Category: Medical

Page: 576

View: 7947

DOWNLOAD NOW »
Molecular, Genetic, and Nutritional Aspects of Major and Trace Minerals is a unique reference that provides a complete overview of the non-vitamin micronutrients, including calcium, copper, iodine, iron, magnesium, manganese, molybdenum, phosphorus, potassium, selenium, sodium, and zinc. In addition, the book covers the nutritional and toxicological properties of nonessential minerals chromium, fluoride and boron, and silicon and vanadium, as well as ultra-trace minerals and those with no established dietary requirement for humans. Users will find in-depth chapters on each essential mineral and mineral metabolism, along with discussions of dietary recommendations in the United States and around the world. Presents the only scientific reference to cover all of the nutritionally relevant essential major and trace minerals Provides a broad introductory chapter on each mineral to give readers valuable background and context Clarifies the cellular and molecular aspects of each mineral and its genetic and genomic aspects Includes coverage of all nutritionally relevant minerals—essential major trace minerals and ultra-trace minerals Underscores the important interactions between minerals so readers learn how metabolism of one mineral influences another

Anatomy ;Ocular physiology ;Biochemistry and genetics ;Pathology ;Microbiology ;Immunology ;Growth and senescence ;Optics ;Therapeutics ;Lasers and instrument technology ;Basic biostatistical and epidemiological terms

Author: Louise Bye,Neil Modi,Miles Stanford

Publisher: OUP Oxford

ISBN: 0199584990

Category: Medical

Page: 288

View: 1127

DOWNLOAD NOW »
An indispensable and fully comprehensive textbook, this covers the basic sciences in ophthalmology and is the only book you need to pass the FRCOphth Part 1 exam.

Bacterial Toxins

Genetics, Cellular Biology and Practical Applications

Author: Thomas Proft

Publisher: Horizon Scientific Press

ISBN: 1908230282

Category: Bacterial toxins

Page: 234

View: 9582

DOWNLOAD NOW »
Toxins are virulence determinants that play an important role in microbial pathogenicity and/or evasion of the host immune response. This makes them ideal targets for the development of novel antimicrobial strategies. The potential applications of toxin research extend beyond simply combating microbial pathogens, and include use as novel anti-cancer drugs and other front-line medicines and as tools in neurobiology. In the field of cellular biology, toxins have become invaluable as tools for the manipulation and investigation of fundamental cellular and physiological processes. Research in this area is thriving and is at a very exciting stage. This timely volume serves as an update on the most important recent advances in the genetics, cellular biology, and practical applications of the most important bacterial toxins. Written by internationally respected scientists, the topics reviewed include: the molecular basis and risk factors for verotoxin pathogenesis * molecular mechanisms of Helicobacter pylori CagA translocation and function * structure and mechanisms of action of pore-forming toxins * bacterial enterotoxins as immunomodulators and vaccine adjuvants * mobile genetic elements as carriers for bacterial virulence genes * the novel family of staphylococcal superantigen-like toxins (SSLs) * new insights into the use of botulinum neurotoxins as therapeutics * microbial toxins as tools in cell biology * the role of the large clostridial cytotoxins in C. difficile disease.

Microbial Population Genetics

Author: Jianping Xu

Publisher: Horizon Scientific Press

ISBN: 190445559X

Category: Science

Page: 213

View: 490

DOWNLOAD NOW »
Microbial population genetics is a rapidly advancing field of investigation with relevance to many areas of science. The subject encompasses theoretical issues, such as the origins and evolution of species, sex, and recombination. Population genetics lays the foundations for tracking the origin and evolution of antibiotic resistance and deadly infectious pathogens and is also an essential tool in the utilization of beneficial microbes. This invaluable book, written by leading researchers in the field, details the current major advances in microbial population genetics and genomics. Distinguished international scientists introduce fundamental concepts, describe genetic tools, and comprehensively review recent data from SNP surveys, whole-genome DNA sequences, and microarray hybridizations. The chapters cover broad groups of microorganisms including viruses, bacteria, archaea, fungi, protozoa, and algae. A major focus is the application of molecular tools in the study of genetic variation. Topics covered include microbial systematics, comparative microbial genomics, horizontal gene transfer, pathogenic bacteria, nitrogen-fixing bacteria, cyanobacteria, microalgae, fungi, malaria parasites, viral pathogens, and metagenomics. Microbial Population Genetics is an essential volume for everyone interested in population genetics, and it is highly recommended reading for all microbiologists.

Physiology and Genetics

Selected Basic and Applied Aspects

Author: Timm Anke,Daniela Weber

Publisher: Springer Science & Business Media

ISBN: 9783642002861

Category: Science

Page: 410

View: 4801

DOWNLOAD NOW »
In the last decade the discipline of mycology has been substantially changed by new research technologies. In particular DNA-based tools for the investigation of fungal taxonomy, signal transduction and regulation, and biosynthetic potential have accelerated advances in mycological knowledge. This volume presents a selection of exciting issues on basic and applied aspects of fungal physiology and genetics. In 18 chapters renowned experts provide an overview of traditional as well as current and future aspects of potential application of fungi in biotechnology. The contributions can be used by scientists to keep up-to-date on the latest developments in the corresponding research area, and by students to familiarize themselves with the different topics.

Bifidobacteria

Genomics and Molecular Aspects

Author: Baltasar Mayo,Douwe van Sinderen

Publisher: Horizon Scientific Press

ISBN: 1904455689

Category: Science

Page: 259

View: 1046

DOWNLOAD NOW »
This title brings together the expertise of leading bifidobacteria experts from around the world to provide an overview of the molecular biology and genomics of this important microbial genus.

Methods for General and Molecular Microbiology

Author: C. A. Reddy,Terry J. Beveridge,John A. Breznak,George Marzluf

Publisher: American Society for Microbiology Press

ISBN: 1555812236

Category: Science

Page: 1069

View: 1022

DOWNLOAD NOW »
A first source for traditional methods of microbiology as well as commonly used modern molecular microbiological methods. • Provides a comprehensive compendium of methods used in general and molecular microbiology. • Contains many new and expanded chapters, including a section on the newly important field of community and genomic analysis. • Provides step-by-step coverage of procedures, with an extensive list of references to guide the user to the original literature for more complete descriptions. • Presents methods for bacteria, archaea, and for the first time a section on mycology. • Numerous schematics and illustrations (both color and black and white) help the reader to easily understand the topics presented.

Environmental Molecular Microbiology

Author: Wen-Tso Liu,Janet K. Jansson

Publisher: Horizon Scientific Press

ISBN: 1904455522

Category: Science

Page: 231

View: 8300

DOWNLOAD NOW »
This book highlights the current state-of-the-art of environmental molecular microbiology. International experts have contributed chapters that describe the various technologies and their applications in environmental microbiology.

Food Microbiology

Fundamentals and Frontiers

Author: Michael P. Doyle,Robert L. Buchanan

Publisher: American Society for Microbiology Press

ISBN: 1555816266

Category: Science

Page: 1138

View: 5058

DOWNLOAD NOW »
This essential reference emphasizes the molecular and mechanistic aspects of food microbiology in one comprehensive volume. • Addresses the field's major concerns, including spoilage, pathogenic bacteria, mycotoxigenic molds, viruses, prions, parasites, preservation methods, fermentation, beneficial microorganisms, and food safety. • Details the latest scientific knowledge and concerns of food microbiology • Offers a description of the latest and most advanced techniques for detecting, analyzing, tracking, and controlling microbiological hazards in food. • Serves as significant reference book for professionals who conduct research, teach food microbiology courses, analyze food samples, conduct epidemiologic investigations, and craft food safety policies.

Medical Microbiology,With STUDENTCONSULT online access,18

Medical Microbiology

Author: David Greenwood

Publisher: Elsevier Health Sciences

ISBN: 0702040894

Category: Medical

Page: 778

View: 8407

DOWNLOAD NOW »
Medical microbiology concerns the nature, distribution and activities of microbes and how they impact on health and wellbeing, most particularly as agents of infection. Infections remain a major global cause of mortality and in most hospitals around one in ten of those admitted will suffer from an infection acquired during their stay. The evolution of microbes presents a massive challenge to modern medicine and public health. The constant changes in viruses such as influenza, HIV, tuberculosis, malaria and SARS demand vigilance and insight into the underlying process. Building on the huge success of previous editions, Medical Microbiology 18/e will inform and inspire a new generation of readers. Now fully revised and updated, initial sections cover the basic biology of microbes, infection and immunity and are followed by a systematic review of infective agents, their associated diseases and their control. A final integrating section addresses the essential principles of diagnosis, treatment and management. An unrivalled collection of international contributors continues to ensure the relevance of the book worldwide and complementary access to the complete online version on Student Consult further enhances the learning experience. Medical Microbiology is explicitly geared to clinical practice and is an ideal textbook for medical and biomedical students and specialist trainees. It will also prove invaluable to medical laboratory scientists and all other busy professionals who require a clear, current and most trusted guide to this fascinating field.

Illustrated Dictionary of Parasitology in the Post-Genomic Era

Author: Hany M. Elsheikha

Publisher: Caister Academic Press

ISBN: 1910190683

Category: Reference

Page: 340

View: 6606

DOWNLOAD NOW »
This illustrated dictionary provides concise definitions and explanations of parasitology terms and related molecular processes presented in an easy-to-use, A-Z order with particular emphasis on terms that are of relevance to parasite biotechnology and molecular biology. With over 4500 entries and more than 170 figures this volume reflects recent, ground-breaking advances in parasitology research. The authors have provided, in a single-volume, an up-to-date glossary of the terminology encountered in contemporary parasitology literature. The dictionary also covers many pertinent terms from related fields of veterinary medicine and life sciences, including microbiology, genetics, biochemistry, biotechnology, infectious diseases, epidemiology, zoonoses, public health, molecular biology, zoology, pharmaceutical science, environmental science, taxonomy and population genetics. This dictionary is highly recommended for students, academic staff, medical and veterinary professionals and life scientists, as well as for members of industrial establishments, governmental agencies and research foundations involved in research activities relating to parasitology and associated scientific fields.